Analysis Note

ControlRat brain tissue lysate

Application

Research Sub CategorySignaling Neuroscience

Research CategoryNeuroscience

Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Serotonin receptor 1A in normal human brain tissue.

Anti-Serotonin receptor 1A Antibody, clone 19A9.2 is an antibody against Serotonin receptor 1A for use in WB, IH.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Serotonin receptor 1A, also known as 5-hydroxytryptamine receptor 1A, is a member of the G protein-coupled receptor family. Serotonin receptor 1A has been found to be expressed highly in the septum and hippocampus. Serotonin receptor 1A seems to have an inhibitory effect on Ca2+ channels, via N-channels and L-channels. The receptor actuates voltage-sensitive slowing using the N-channels and actuates steady state inhibition using the L-channels.

Immunogen

KLH-conjugated linear peptide corresponding to rat Serotonin receptor 1A.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Ion Exchange

Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Format: Purified

Quality

Evaluated by Western Blot in rat brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Serotonin receptor 1A on 10 µg of rat brain tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~40 kDa observed. The calculated molecular weight is 46 kDa